WFDC12

Across TCGA patient cohorts, WFDC12 protein abundance is significantly associated with the RNA expression of many other genes, with 4,708 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible WFDC12-associated genes across cancer lineages are GMPR, MGST3, and PIP4K2A. Each is linked with WFDC12 in more than 1 cancer types. Because this analysis shows association rather than direction, both WFDC12-to-partner and partner-to-WFDC12 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, WFDC12 versus GMPR in LSCC, with a Pearson correlation of -0.88.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WFDC12→partner) and Y-score (partner→WFDC12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	GMPR →	-1.376	-1.033	.001	.005	3	2
LSCC	MGST3 →	-0.835	-0.748	.002	.002	3	2
HNSC	PIP4K2A →	-1.041	-1.933	<.001	<.001	3	2
LSCC	SLC66A3 →	-1.073	-0.748	.001	.002	3	2
HNSC	PNPLA1 →	+0.982	+1.567	<.001	<.001	3	2
LSCC	NCCRP1 →	+2.458	+0.748	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,708 associations by consensus.

WFDC12 vs GMPR — LSCC

Explore this scatter interactively →