WFDC12

Across TCGA patient cohorts, WFDC12 mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible WFDC12-associated genes across cancer lineages are Hepatocytes and Th1 cells. Each is linked with WFDC12 in more than 1 cancer types. Because this analysis shows association rather than direction, both WFDC12-to-partner and partner-to-WFDC12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Hepatocytes grouped by WFDC12-low versus WFDC12-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WFDC12→partner) and Y-score (partner→WFDC12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Hepatocytes →	-0.011	-2.820	.049	.040	3	1
UCEC	Th1 cells →	+0.109	+3.321	.026	.010	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Hepatocytes by WFDC12 expression — UCEC

Explore this box plot interactively →