WFDC10A

Across TCGA patient cohorts, WFDC10A RNA expression is significantly associated with the go_rna of many other GO terms, with 6,829 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible WFDC10A-associated GO terms across cancer lineages are Proton transmembrane transport, Oxidative phosphorylation, and Aerobic respiration. Each is linked with WFDC10A in more than 10 cancer types. Because this analysis shows association rather than direction, both WFDC10A-to-partner and partner-to-WFDC10A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Proton transmembrane transport grouped by WFDC10A-low versus WFDC10A-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (WFDC10A→partner) and Y-score (partner→WFDC10A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Proton transmembrane transport →	+0.044	+0.226	<.001	<.001	3	11
STAD	Oxidative phosphorylation →	+0.090	+0.311	<.001	<.001	3	11
ESCA	Aerobic respiration →	+0.078	+0.321	<.001	.003	3	11
STAD	Ribose phosphate biosynthetic process →	+0.069	+0.258	<.001	.001	3	11
ESCA	Transition metal ion transport →	+0.071	+0.320	<.001	<.001	3	10
STAD	Lysosomal lumen acidification →	+0.045	+0.205	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,829 associations by consensus.

Proton transmembrane transport by WFDC10A expression — ESCA

Explore this box plot interactively →