Across TCGA patient cohorts, WEE2 mutation is significantly associated with the RNA expression of many other genes, with 4,619 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible WEE2-associated genes across cancer lineages are RNU1-35P, HSFY1, and STOML2. Each is linked with WEE2 in more than 3 cancer types. Because this analysis shows association rather than direction, both WEE2-to-partner and partner-to-WEE2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WEE2→partner) and Y-score (partner→WEE2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	RNU1-35P →	+0.646	+4.314	<.001	.009	3	4
READ	HSFY1 →	+0.011	+4.341	<.001	.007	3	3
UCEC	STOML2 →	+0.364	+2.545	.002	<.001	3	3
HNSC	RN7SKP190 →	+0.133	+4.526	<.001	.007	3	3
UCEC	MLLT10P2 →	+0.093	+1.827	<.001	.008	3	3
SKCM	LINC02085 →	+0.228	+1.946	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,619 associations by consensus.

Exploration

WEE2 survival (RNA) · tumor vs normal (RNA) · all WEE2 data types