WDR93

Across TCGA patient cohorts, WDR93 mutation is significantly associated with the total protein of many other genes, with 28 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible WDR93-associated genes across cancer lineages are INPP4B, PCNA, and Rictor_pT1135. Each is linked with WDR93 in more than 1 cancer types. Because this analysis shows association rather than direction, both WDR93-to-partner and partner-to-WDR93 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, INPP4B grouped by WDR93-low versus WDR93-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WDR93→partner) and Y-score (partner→WDR93) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	INPP4B →	-0.290	-2.584	.029	.010	3	2
UCEC	PCNA →	+0.278	+2.807	.001	.003	3	2
UCEC	Rictor_pT1135 →	-0.091	-1.807	.032	.027	3	2
UCEC	STAT3_pY705 →	-0.371	-1.807	<.001	.027	3	2
SKCM	Lck →	-0.304	-2.222	.031	.010	3	2
SKCM	p21 →	-0.540	-3.000	.003	.034	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 28 associations by consensus.

INPP4B by WDR93 expression — UCEC

Explore this box plot interactively →