WDR93

Across TCGA pan-cancer cohorts, WDR93 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated WDR93 data layer compared with 4 for mutation status.

The strongest signal is observed in breast invasive carcinoma (BRCA), where higher WDR93 RNA is associated with better overall survival. In most high-consensus cancer types, elevated WDR93 expression acts as an unfavorable survival marker, although some lineages such as BRCA and KIRP show a favorable association.

BRCA, KIRP, and LGG are the cancer types where WDR93 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BRCA	OS	Median	All	0.950	0.897	<.001	77	view →
KIRP	DFS	Tertile	All	1.000	0.738	.005	47	view →
LGG	DFS	Median	All	0.784	0.875	<.001	41	view →
CHOL	OS	Median	All	0.382	0.856	.005	24	view →
UCS	DFS	Tertile	II,III,IV	0.552	0.118	.009	22	view →
LIHC	OS	Quartile	All	0.396	0.606	.003	22	view →
ESCA	OS	Median	All	0.403	0.597	.013	15	view →
UVM	DFS	Quartile	All	0.775	0.502	.011	14	view →
COAD	OS	Quartile	All	0.579	0.798	.011	13	view →
DLBC	DFS	Median	IV	0.281	1.000	.005	12	view →
HNSC	DFS	Quartile	IV	0.723	0.368	.004	9	view →
THCA	DFS	Median	All	0.899	0.779	.001	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

WDR93–BRCA (OS)

Open the BRCA breakdown →