WDR93

Across TCGA cell cohorts, WDR93 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible WDR93-associated genes across cancer lineages are CLPS, OR6C70, and FAM25G. Each is linked with WDR93 in more than 1 cancer types. Because this analysis shows association rather than direction, both WDR93-to-partner and partner-to-WDR93 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CLPS grouped by WDR93-low versus WDR93-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WDR93→partner) and Y-score (partner→WDR93) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	CLPS →	+0.211	+3.217	<.001	.006	3	1
SKIN	OR6C70 →	+0.045	+3.217	<.001	.006	3	1
SKIN	FAM25G →	+0.358	+3.217	<.001	.006	3	1
SKIN	PRRT1B →	+0.032	+3.376	<.001	.002	3	1
LARGE_INTESTINE	LILRA5 →	+0.038	+4.977	<.001	.007	3	1
SKIN	CDH16 →	+0.120	+2.940	<.001	.007	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

CLPS by WDR93 expression — SKIN

Explore this box plot interactively →