WDR92

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, WDR92 mutation is significantly associated with the RNA expression of many other genes, with 166 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible WDR92-associated genes across cancer lineages are LINC01919, MIR4753, and RN7SL326P. Each is linked with WDR92 in more than 1 cancer types. Because this analysis shows association rather than direction, both WDR92-to-partner and partner-to-WDR92 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC01919 grouped by WDR92-low versus WDR92-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WDR92→partner) and Y-score (partner→WDR92) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECLINC01919 →+0.192+4.695<.001<.00131
UCECMIR4753 →+1.177+3.454<.001.00631
UCECRN7SL326P →+0.254+4.453.008<.00131
UCECMIR4262 →+0.556+4.226<.001.00831
UCECMIR4524B →+0.544+3.418<.001.00931
UCECRN7SL300P →+0.401+4.695<.001<.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 166 associations by consensus.

LINC01919 by WDR92 expression — UCEC

Box plot of LINC01919 in WDR92-low vs WDR92-high samples in UCEC.

Explore this box plot interactively →

Exploration