WDR91

Across TCGA pan-cancer cohorts, WDR91 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated WDR91 data layer compared with 24 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher WDR91 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated WDR91 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and LUAD show a favorable association.

CCRCC, UCEC, and LUAD are the cancer types where WDR91 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	OS	Tertile	III,IV	0.946	0.699	.019	13	view →
UCEC	OS	Tertile	II,III,IV	0.554	1.000	.013	8	view →
LUAD	DFS	Quartile	All	0.746	0.450	.019	5	view →
PDAC	DFS	Median	IV	0.245	0.766	.017	3	view →
HNSC	DFS	Median	IV	0.889	0.407	.042	3	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

WDR91–CCRCC (OS)

Open the CCRCC breakdown →