WDR91

Across TCGA patient cohorts, WDR91 mutation is significantly associated with the RNA expression of many other genes, with 5,028 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible WDR91-associated genes across cancer lineages are GOLGA6L11P, PKN3, and ZMYND19. Each is linked with WDR91 in more than 2 cancer types. Because this analysis shows association rather than direction, both WDR91-to-partner and partner-to-WDR91 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GOLGA6L11P grouped by WDR91-low versus WDR91-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WDR91→partner) and Y-score (partner→WDR91) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	GOLGA6L11P →	+0.051	+5.303	<.001	.006	3	3
UCEC	PKN3 →	+0.829	+2.765	<.001	<.001	3	3
UCEC	ZMYND19 →	+0.506	+2.091	<.001	<.001	3	3
UCEC	JKAMP →	+0.408	+3.732	.002	<.001	3	3
UCEC	MSANTD3 →	+0.513	+2.086	<.001	<.001	3	3
UCEC	IARS2 →	+0.631	+3.721	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,028 associations by consensus.

GOLGA6L11P by WDR91 expression — HNSC

Explore this box plot interactively →