WDR91

Across TCGA cell cohorts, WDR91 mutation is significantly associated with the RNA expression of many other genes, with 337 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible WDR91-associated genes across cancer lineages are USP50, SPEM3, and CYB5D1. Each is linked with WDR91 in more than 1 cancer types. Because this analysis shows association rather than direction, both WDR91-to-partner and partner-to-WDR91 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, USP50 grouped by WDR91-low versus WDR91-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WDR91→partner) and Y-score (partner→WDR91) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	USP50 →	+0.064	+3.624	.006	.005	3	2
OVARY	SPEM3 →	+0.027	+3.949	<.001	.001	3	2
LARGE_INTESTINE	CYB5D1 →	+0.825	+3.064	.004	.009	3	2
PANCREAS	TBL1Y →	+0.005	+4.614	<.001	.004	3	1
URINARY_TRACT	PRRG3 →	+0.006	+5.087	<.001	.004	3	1
URINARY_TRACT	PABPC1L2B →	+0.013	+5.087	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 337 associations by consensus.

USP50 by WDR91 expression — OVARY

Explore this box plot interactively →