WDR90

Across TCGA cell cohorts, WDR90 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,952 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible WDR90-associated GO terms across cancer lineages are Actomyosin contractile ring organization, Telomeric loop disassembly, and Positive regulation of DNA-directed DNA polymerase activity. Each is linked with WDR90 in more than 14 cancer types. Because this analysis shows association rather than direction, both WDR90-to-partner and partner-to-WDR90 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Actomyosin contractile ring organization grouped by WDR90-low versus WDR90-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (WDR90→partner) and Y-score (partner→WDR90) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Actomyosin contractile ring organization →	+0.176	+1.231	<.001	<.001	3	15
BONE	Telomeric loop disassembly →	+0.134	+1.525	<.001	<.001	3	14
SOFT_TISSUE	Positive regulation of DNA-directed DNA polymerase activity →	+0.210	+1.795	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Taurine biosynthetic process →	+0.885	+1.107	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Alkanesulfonate biosynthetic process →	+0.885	+1.107	<.001	<.001	3	14
BONE	Leading strand elongation →	+0.153	+1.575	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,952 associations by consensus.

Actomyosin contractile ring organization by WDR90 expression — SKIN

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