WDR90

Across TCGA cell cohorts, WDR90 mutation is significantly associated with the RNA expression of many other genes, with 1,024 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible WDR90-associated genes across cancer lineages are ADPRM, VSTM2B, and INSL4. Each is linked with WDR90 in more than 2 cancer types. Because this analysis shows association rather than direction, both WDR90-to-partner and partner-to-WDR90 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ADPRM grouped by WDR90-low versus WDR90-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WDR90→partner) and Y-score (partner→WDR90) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	ADPRM →	+0.607	+2.437	.001	.007	3	3
OESOPHAGUS	VSTM2B →	+0.129	+4.392	<.001	.003	3	2
SOFT_TISSUE	INSL4 →	+0.112	+3.415	<.001	.004	3	2
LUNG_NSCLC_LUAD	SLCO1B7 →	+0.924	+2.341	<.001	.005	3	2
BLOOD_Leukemia	CENPM →	+0.545	+2.614	.008	.003	3	2
BLOOD_Leukemia	ENO3 →	+0.803	+3.367	.002	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,024 associations by consensus.

ADPRM by WDR90 expression — BLOOD_Leukemia

Explore this box plot interactively →