WDR87

Across TCGA patient cohorts, WDR87 mutation is significantly associated with the RNA expression of many other genes, with 3,081 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible WDR87-associated genes across cancer lineages are GBP5, XPNPEP1, and IFNG. Each is linked with WDR87 in more than 3 cancer types. Because this analysis shows association rather than direction, both WDR87-to-partner and partner-to-WDR87 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GBP5 grouped by WDR87-low versus WDR87-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WDR87→partner) and Y-score (partner→WDR87) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	GBP5 →	+0.928	+1.435	<.001	<.001	3	4
UCEC	XPNPEP1 →	+0.298	+1.271	<.001	.001	3	4
UCEC	IFNG →	+0.618	+1.467	<.001	<.001	3	4
UCEC	CXCL9 →	+1.660	+1.640	<.001	<.001	3	4
UCEC	CCL4 →	+0.646	+1.243	<.001	<.001	3	4
BRCA	IL21 →	+0.451	+4.376	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,081 associations by consensus.

GBP5 by WDR87 expression — UCEC

Explore this box plot interactively →