WDR87

Across TCGA pan-cancer cohorts, WDR87 RNA is linked to patient survival in 18 of 34 cancer types, making it the most broadly survival-associated WDR87 data layer compared with 5 for mutation status and 1 for mass-spec protein.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher WDR87 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated WDR87 expression acts as an unfavorable survival marker, although some lineages such as UVM and UCS show a favorable association.

KIRP, UVM, and UCS are the cancer types where WDR87 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	DFS	Median	All	0.784	0.922	<.001	137	view →
UVM	DFS	Median	All	0.792	0.380	<.001	114	view →
UCS	DFS	Median	II,III,IV	0.570	0.142	<.001	54	view →
LGG	OS	Tertile	All	0.947	0.833	<.001	32	view →
CESC	DFS	Quartile	All	0.857	0.680	.010	22	view →
PAAD	OS	Tertile	All	0.501	0.207	.005	18	view →
LUAD	OS	Median	III,IV	0.444	0.221	.022	16	view →
KIRC	DFS	Tertile	II,III,IV	0.362	0.585	.016	15	view →
GBM	DFS	Tertile	All	0.331	0.215	.018	15	view →
ACC	OS	Tertile	III,IV	0.355	0.686	.003	12	view →
CHOL	DFS	Quartile	II,III,IV	1.000	0.147	.035	9	view →
BLCA	OS	Tertile	All	0.645	0.232	.032	8	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 18 lineages.

WDR87–KIRP (DFS)

Open the KIRP breakdown →