WDR87

Across TCGA patient cohorts, WDR87 mutation is significantly associated with the total protein of many other genes, with 57 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible WDR87-associated genes across cancer lineages are Caspase-7-cleavedD198, GAPDH, and MEK1. Each is linked with WDR87 in more than 4 cancer types. Because this analysis shows association rather than direction, both WDR87-to-partner and partner-to-WDR87 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Caspase-7-cleavedD198 grouped by WDR87-low versus WDR87-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WDR87→partner) and Y-score (partner→WDR87) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	Caspase-7-cleavedD198 →	+1.174	+3.467	<.001	<.001	3	5
COAD	GAPDH →	+0.329	+1.874	.045	.047	3	3
UCEC	MEK1 →	+0.322	+1.906	<.001	<.001	3	2
COAD	p62 Lck ligand →	+0.250	+1.807	.047	.024	3	2
COAD	14-3-3_epsilon →	+0.089	+2.025	.032	.016	3	2
COAD	PREX1 →	+0.154	+2.355	.022	.017	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 57 associations by consensus.

Caspase-7-cleavedD198 by WDR87 expression — COAD

Explore this box plot interactively →