WDR86

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, WDR86 mutation is significantly associated with the immune_cell of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible WDR86-associated genes across cancer lineages are Neurons, HSC, and B-cells. Each is linked with WDR86 in more than 1 cancer types. Because this analysis shows association rather than direction, both WDR86-to-partner and partner-to-WDR86 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WDR86→partner) and Y-score (partner→WDR86) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMNeurons →+0.025+2.826.030.03631
UCECHSC →+0.130+2.815.039.03631
UCECB-cells →+0.031+1.895.043.04831
UCECCD4+ memory T-cells →+0.023+3.370.025.00131
Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Exploration