WDR86-AS1

Across TCGA pan-cancer cohorts, WDR86-AS1 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated WDR86-AS1 data layer.

The strongest signal is observed in skin cutaneous melanoma (SKCM), where higher WDR86-AS1 RNA is associated with better overall survival. In most high-consensus cancer types, elevated WDR86-AS1 expression acts as an unfavorable survival marker, although some lineages such as SKCM and HNSC show a favorable association.

SKCM, HNSC, and LUAD are the cancer types where WDR86-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SKCM	OS	Median	All	0.405	0.279	<.001	109	view →
HNSC	DFS	Median	IV	0.420	0.246	.003	56	view →
LUAD	DFS	Median	II,III,IV	0.758	0.603	.002	53	view →
LIHC	OS	Tertile	All	0.819	0.677	.001	44	view →
STAD	OS	Median	All	0.599	0.734	.007	41	view →
BRCA	OS	Tertile	III,IV	0.722	0.466	.007	35	view →
LGG	OS	Tertile	All	0.609	0.358	<.001	33	view →
ESCA	DFS	Median	III,IV	0.474	0.228	.004	30	view →
UCS	DFS	Median	IV	0.885	0.440	.015	30	view →
THCA	OS	Quartile	All	1.000	0.601	.009	30	view →
KIRP	OS	Tertile	II,III,IV	0.578	1.000	.022	29	view →
KIRC	DFS	Tertile	All	0.871	0.728	.019	22	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

WDR86-AS1–SKCM (OS)

Open the SKCM breakdown →