WDR86-AS1

Across TCGA pan-cancer cohorts, WDR86-AS1 RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of WDR86-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where WDR86-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types WDR86-AS1 is over-expressed in tumor, although a few such as KICH and LUSC show the opposite, repressed pattern.

KICH, LUSC, and COAD are the cancer types where WDR86-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in WDR86-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	Male	All	−1.720	<.001	10	view →
LUSC	Female	All	−2.072	<.001	8	view →
COAD	All	II,III,IV	−0.302	<.001	8	view →
BRCA	Female	II,III,IV	−2.005	<.001	6	view →
KIRP	Male	All	−0.683	<.001	6	view →
LUAD	All	II,III,IV	−0.998	.007	5	view →
THCA	Male	All	+0.941	<.001	5	view →
READ	Female	All	−0.904	.021	2	view →
PRAD	All	All	−0.333	.015	2	view →
KIRC	Female	IV	−0.720	.006	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

WDR86-AS1–KICH

Open the KICH breakdown →