WDR83OS

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, WDR83OS mutation is significantly associated with the RNA expression of many other genes, with 28 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible WDR83OS-associated genes across cancer lineages are MIR6877, CYB5AP5, and MIR3152. Each is linked with WDR83OS in more than 1 cancer types. Because this analysis shows association rather than direction, both WDR83OS-to-partner and partner-to-WDR83OS results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR6877 grouped by WDR83OS-low versus WDR83OS-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WDR83OS→partner) and Y-score (partner→WDR83OS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECMIR6877 →+0.684+3.048<.001.00631
SKCMCYB5AP5 →+0.094+7.816<.001.00831
SKCMMIR3152 →+0.478+7.816<.001.00831
SKCMMIR3167 →+0.603+7.816<.001.00831
SKCMMRPS5P4 →+0.139+7.816<.001.00831
UCECRNA5SP175 →+1.311+3.096<.001.00431
Each partner links to its Q-omics profile. Showing the 6 strongest of 28 associations by consensus.

MIR6877 by WDR83OS expression — UCEC

Box plot of MIR6877 in WDR83OS-low vs WDR83OS-high samples in UCEC.

Explore this box plot interactively →

Exploration