WDR83OS

Across TCGA pan-cancer cohorts, WDR83OS RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of WDR83OS’s most consistent transcriptional readouts.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where WDR83OS RNA is more highly expressed in tumor relative to normal tissue. In most cancer types WDR83OS is over-expressed in tumor, although a few such as LUAD and KICH show the opposite, repressed pattern.

LIHC, HNSC, and LUAD are the cancer types where WDR83OS tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in WDR83OS RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LIHC	Female	II,III,IV	+0.766	<.001	9	view →
HNSC	Male	III,IV	+0.468	<.001	8	view →
LUAD	All	All	−0.292	<.001	8	view →
COAD	Female	All	+0.408	<.001	7	view →
BRCA	All	All	+0.213	<.001	6	view →
KICH	Female	All	−0.659	<.001	5	view →
BLCA	All	All	+0.397	.011	5	view →
CHOL	All	All	+1.441	<.001	3	view →
LUSC	Male	III,IV	−0.439	.009	2	view →
ESCA	All	All	+0.470	.010	1	view →
KIRC	Female	IV	+0.293	.030	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

WDR83OS–LIHC

Open the LIHC breakdown →