WDR83

Across TCGA patient cohorts, WDR83 mutation is significantly associated with the RNA expression of many other genes, with 178 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible WDR83-associated genes across cancer lineages are RNU6-1145P, FAM197Y4, and GBP5. Each is linked with WDR83 in more than 1 cancer types. Because this analysis shows association rather than direction, both WDR83-to-partner and partner-to-WDR83 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-1145P grouped by WDR83-low versus WDR83-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WDR83→partner) and Y-score (partner→WDR83) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	RNU6-1145P →	+0.261	+5.033	<.001	.003	3	2
SKCM	FAM197Y4 →	+0.179	+7.816	<.001	.008	3	1
UCEC	GBP5 →	+1.328	+3.818	<.001	<.001	3	1
UCEC	NTAN1 →	+0.468	+3.346	.003	.005	3	1
UCEC	RNF166 →	+0.468	+3.499	.001	.002	3	1
UCEC	ATP6V0D1 →	+0.636	+2.711	.004	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 178 associations by consensus.

RNU6-1145P by WDR83 expression — BLCA

Explore this box plot interactively →