WDR82

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, WDR82 mutation is significantly associated with the RNA expression of many other genes, with 1,968 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible WDR82-associated genes across cancer lineages are RNA5SP329, RN7SKP96, and SMIM28. Each is linked with WDR82 in more than 2 cancer types. Because this analysis shows association rather than direction, both WDR82-to-partner and partner-to-WDR82 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP329 grouped by WDR82-low versus WDR82-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WDR82→partner) and Y-score (partner→WDR82) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUSCRNA5SP329 →+0.404+5.517<.001<.00133
BRCARN7SKP96 →+0.217+3.459.001.00932
UCECSMIM28 →+0.186+1.728.002.00232
LUSCRNU6-358P →+0.409+4.548.003.00932
SKCMRPL17P19 →+0.063+5.080<.001.00431
UCECPGAP2 →+0.408+2.534<.001<.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,968 associations by consensus.

RNA5SP329 by WDR82 expression — LUSC

Box plot of RNA5SP329 in WDR82-low vs WDR82-high samples in LUSC.

Explore this box plot interactively →

Exploration