WDR81

Across TCGA patient cohorts, WDR81 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,170 significant associations in total. OV shows the largest number of these associations.

The most reproducible WDR81-associated GO terms across cancer lineages are Positive regulation of pinocytosis, Piecemeal microautophagy of the nucleus, and Regulation of lysosome organization. Each is linked with WDR81 in more than 30 cancer types. Because this analysis shows association rather than direction, both WDR81-to-partner and partner-to-WDR81 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of pinocytosis grouped by WDR81-low versus WDR81-high in SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (WDR81→partner) and Y-score (partner→WDR81) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SCLC	Positive regulation of pinocytosis →	+0.153	+1.826	<.001	.001	3	31
SCLC	Piecemeal microautophagy of the nucleus →	+0.098	+1.675	<.001	<.001	3	30
CHOL	Regulation of lysosome organization →	+0.065	+0.994	<.001	<.001	3	29
SCLC	Protein autophosphorylation →	+0.058	+1.893	<.001	<.001	3	29
SCLC	Regulation of small GTPase mediated signal transduction →	+0.043	+1.757	<.001	<.001	3	29
SCLC	Activation of GTPase activity →	+0.053	+2.469	<.001	<.001	3	29

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,170 associations by consensus.

Positive regulation of pinocytosis by WDR81 expression — SCLC

Explore this box plot interactively →