WDR81

Across TCGA patient cohorts, WDR81 mutation is significantly associated with the RNA expression of many other genes, with 3,675 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible WDR81-associated genes across cancer lineages are NDUFC1, SLF1, and NDUFS4. Each is linked with WDR81 in more than 2 cancer types. Because this analysis shows association rather than direction, both WDR81-to-partner and partner-to-WDR81 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NDUFC1 grouped by WDR81-low versus WDR81-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WDR81→partner) and Y-score (partner→WDR81) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	NDUFC1 →	+0.340	+2.000	.001	.009	3	3
COAD	SLF1 →	+0.387	+2.232	.001	.005	3	3
UCEC	NDUFS4 →	+0.344	+1.273	.002	.001	3	3
COAD	CXCL11 →	+1.823	+3.584	<.001	.002	3	3
UCEC	DNAJA1 →	+0.368	+1.916	.003	.001	3	3
COAD	CA9 →	+1.716	+2.000	.001	.009	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,675 associations by consensus.

NDUFC1 by WDR81 expression — COAD

Explore this box plot interactively →