WDR81

Across TCGA cell cohorts, WDR81 mutation is significantly associated with the RNA expression of many other genes, with 846 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible WDR81-associated genes across cancer lineages are CCNF, ZNF839, and TMEM89. Each is linked with WDR81 in more than 2 cancer types. Because this analysis shows association rather than direction, both WDR81-to-partner and partner-to-WDR81 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CCNF grouped by WDR81-low versus WDR81-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WDR81→partner) and Y-score (partner→WDR81) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	CCNF →	+0.598	+3.234	.007	.004	3	3
LARGE_INTESTINE	ZNF839 →	+0.613	+3.386	.005	.001	3	3
OVARY	TMEM89 →	+0.132	+3.378	<.001	.006	3	2
BREAST	SIGLECL1 →	+0.016	+4.196	<.001	.006	3	2
STOMACH	PF4V1 →	+0.835	+4.432	<.001	.003	3	2
STOMACH	C1orf146 →	+0.036	+4.432	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 846 associations by consensus.

CCNF by WDR81 expression — LARGE_INTESTINE

Explore this box plot interactively →