WDR75

Across TCGA patient cohorts, WDR75 protein abundance is significantly associated with the RNA expression of many other genes, with 21,491 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible WDR75-associated genes across cancer lineages are MYBL2, FOXM1, and HROB. Each is linked with WDR75 in more than 8 cancer types. Because this analysis shows association rather than direction, both WDR75-to-partner and partner-to-WDR75 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, WDR75 versus MYBL2 in BRCA, with a Pearson correlation of 0.58.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WDR75→partner) and Y-score (partner→WDR75) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MYBL2 →	+1.502	+0.332	<.001	<.001	3	9
BRCA	FOXM1 →	+1.252	+0.326	<.001	<.001	3	9
LSCC	HROB →	+0.955	+0.417	<.001	<.001	3	9
UCEC	PKMYT1 →	+0.898	+0.258	<.001	<.001	3	9
BRCA	ABCA8 →	-1.021	-0.363	<.001	<.001	3	9
BRCA	CDCA5 →	+1.263	+0.362	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 21,491 associations by consensus.

WDR75 vs MYBL2 — BRCA

Explore this scatter interactively →