WDR73

Across TCGA patient cohorts, WDR73 mutation is significantly associated with the total protein of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible WDR73-associated genes across cancer lineages are Ku80, PRAS40_pT246, and Myosin-IIa_pS1943. Each is linked with WDR73 in more than 1 cancer types. Because this analysis shows association rather than direction, both WDR73-to-partner and partner-to-WDR73 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Ku80 grouped by WDR73-low versus WDR73-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WDR73→partner) and Y-score (partner→WDR73) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Ku80 →	+0.291	+2.820	.044	.036	3	1
UCEC	PRAS40_pT246 →	+0.231	+2.820	.028	.036	3	1
UCEC	Myosin-IIa_pS1943 →	+0.337	+2.820	.007	.036	1	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Ku80 by WDR73 expression — UCEC

Explore this box plot interactively →