WDR64

Across TCGA cell cohorts, WDR64 mutation is significantly associated with the RNA expression of many other genes, with 69 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible WDR64-associated genes across cancer lineages are OR1L6, CFHR2, and H4C7. Each is linked with WDR64 in more than 1 cancer types. Because this analysis shows association rather than direction, both WDR64-to-partner and partner-to-WDR64 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR1L6 grouped by WDR64-low versus WDR64-high in BONE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WDR64→partner) and Y-score (partner→WDR64) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	OR1L6 →	+0.020	+5.169	<.001	.004	3	2
BLOOD_Leukemia	CFHR2 →	+0.296	+4.539	<.001	.007	3	2
BLOOD_Lymphoma	H4C7 →	+0.142	+5.247	<.001	.001	3	2
LUNG_NSCLC_LUAD	MT1B →	+0.672	+4.082	<.001	.001	3	2
LUNG_NSCLC_LUAD	C10orf120 →	+0.013	+3.362	<.001	.007	3	2
BONE	HES3 →	+0.053	+5.169	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 69 associations by consensus.

OR1L6 by WDR64 expression — BONE

Explore this box plot interactively →