WDR64

Across TCGA pan-cancer cohorts, WDR64 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated WDR64 data layer compared with 9 for mutation status.

The strongest signal is observed in kidney chromophobe (KICH), where higher WDR64 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated WDR64 expression acts as an unfavorable survival marker, although some lineages such as HNSC and SKCM show a favorable association.

KICH, HNSC, and THCA are the cancer types where WDR64 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	OS	Quartile	II,III,IV	0.753	1.000	<.001	104	view →
HNSC	DFS	Tertile	III,IV	0.749	0.571	<.001	46	view →
THCA	OS	Median	III,IV	0.939	1.000	.002	34	view →
SKCM	DFS	Median	All	0.255	0.154	<.001	29	view →
BRCA	DFS	Quartile	All	0.967	0.924	.002	23	view →
ESCA	DFS	Median	All	0.613	0.455	.012	22	view →
CESC	DFS	Median	II,III,IV	0.876	0.700	.007	14	view →
DLBC	DFS	Median	All	0.584	1.000	.004	13	view →
KIRP	DFS	Median	IV	0.041	0.592	.038	12	view →
LAML	DFS	Quartile	All	0.230	0.632	.005	12	view →
GBM	OS	Quartile	All	0.228	0.391	.008	11	view →
OV	OS	Tertile	All	0.741	0.648	.012	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

WDR64–KICH (OS)

Open the KICH breakdown →