WDR61

Across TCGA patient cohorts, WDR61 mutation is significantly associated with the RNA expression of many other genes, with 1,566 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible WDR61-associated genes across cancer lineages are RALBP1P1, RNA5SP408, and MIR7702. Each is linked with WDR61 in more than 1 cancer types. Because this analysis shows association rather than direction, both WDR61-to-partner and partner-to-WDR61 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RALBP1P1 grouped by WDR61-low versus WDR61-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WDR61→partner) and Y-score (partner→WDR61) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RALBP1P1 →	+0.104	+3.937	.004	.004	3	2
LUAD	RNA5SP408 →	+0.308	+7.930	<.001	.008	3	2
UCEC	MIR7702 →	+0.163	+3.738	<.001	.009	3	2
UCEC	FDX1P2 →	+0.124	+2.702	<.001	<.001	3	2
UCEC	NDUFB10P1 →	+0.140	+1.755	.003	.004	3	2
COAD	RNU6-1127P →	+0.271	+4.399	.004	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,566 associations by consensus.

RALBP1P1 by WDR61 expression — COAD

Explore this box plot interactively →