WDR61

Across TCGA cell cohorts, WDR61 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,233 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible WDR61-associated GO terms across cancer lineages are Tricarboxylic acid metabolic process, Isocitrate metabolic process, and RNA import into nucleus. Each is linked with WDR61 in more than 11 cancer types. Because this analysis shows association rather than direction, both WDR61-to-partner and partner-to-WDR61 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Tricarboxylic acid metabolic process grouped by WDR61-low versus WDR61-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (WDR61→partner) and Y-score (partner→WDR61) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Tricarboxylic acid metabolic process →	+0.109	+0.578	<.001	<.001	3	12
SKIN	Isocitrate metabolic process →	+0.139	+0.853	<.001	<.001	3	11
KIDNEY	RNA import into nucleus →	+0.114	+0.637	<.001	.002	3	11
UPPER_AERODIGESTIVE_TRACT	Mitotic sister chromatid cohesion →	+0.119	+0.979	<.001	<.001	3	10
BLOOD_Myeloma	Resolution of DNA recombination intermediates →	+0.169	+0.519	.001	.006	3	10
BREAST	Gastrulation →	-0.103	-1.019	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,233 associations by consensus.

Tricarboxylic acid metabolic process by WDR61 expression — KIDNEY

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