WDR55

Across TCGA patient cohorts, WDR55 protein abundance is significantly associated with the RNA expression of many other genes, with 7,287 significant associations in total. GBM shows the largest number of these associations.

The most reproducible WDR55-associated genes across cancer lineages are ATP6V0E1, ETF1, and HDAC3. Each is linked with WDR55 in more than 3 cancer types. Because this analysis shows association rather than direction, both WDR55-to-partner and partner-to-WDR55 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, WDR55 versus ATP6V0E1 in UCEC, with a Pearson correlation of 0.29.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WDR55→partner) and Y-score (partner→WDR55) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ATP6V0E1 →	+0.616	+0.201	.003	.001	3	4
UCEC	ETF1 →	+0.475	+0.237	.002	<.001	3	4
UCEC	HDAC3 →	+0.471	+0.185	.002	.006	3	4
GBM	PTGDS →	-1.543	-0.349	<.001	<.001	3	3
HNSC	KMT5B →	-0.432	-0.165	.004	.003	3	3
UCEC	CLCN3P1 →	-0.959	-0.290	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,287 associations by consensus.

WDR55 vs ATP6V0E1 — UCEC

Explore this scatter interactively →