WDR55

Across TCGA cell cohorts, WDR55 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,642 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible WDR55-associated GO terms across cancer lineages are Metaphase/anaphase transition of cell cycle, Metaphase/anaphase transition of mitotic cell cycle, and Cytosolic transport. Each is linked with WDR55 in more than 13 cancer types. Because this analysis shows association rather than direction, both WDR55-to-partner and partner-to-WDR55 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Metaphase/anaphase transition of cell cycle grouped by WDR55-low versus WDR55-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (WDR55→partner) and Y-score (partner→WDR55) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Metaphase/anaphase transition of cell cycle →	+0.151	+0.490	.005	<.001	3	14
SOFT_TISSUE	Metaphase/anaphase transition of mitotic cell cycle →	+0.162	+0.856	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Cytosolic transport →	+0.064	+0.692	<.001	.001	3	12
SOFT_TISSUE	Pre-mRNA catabolic process →	+0.125	+0.700	<.001	<.001	3	12
BONE	Viral translational termination-reinitiation →	+0.084	+0.501	<.001	<.001	3	12
BLOOD_Lymphoma	mRNA splice site recognition →	+0.124	+0.654	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,642 associations by consensus.

Metaphase/anaphase transition of cell cycle by WDR55 expression — BONE

Explore this box plot interactively →