WDR48

Across TCGA patient cohorts, WDR48 protein abundance is significantly associated with the RNA expression of many other genes, with 7,459 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible WDR48-associated genes across cancer lineages are CLASP2, SLC25A26, and MKRN2. Each is linked with WDR48 in more than 6 cancer types. Because this analysis shows association rather than direction, both WDR48-to-partner and partner-to-WDR48 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, WDR48 versus CLASP2 in BRCA, with a Pearson correlation of 0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WDR48→partner) and Y-score (partner→WDR48) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CLASP2 →	+0.423	+0.124	<.001	<.001	3	7
HNSC	SLC25A26 →	+0.416	+0.166	<.001	.002	3	6
BRCA	MKRN2 →	+0.445	+0.160	<.001	<.001	3	6
BRCA	TSEN2 →	+0.650	+0.194	<.001	<.001	3	6
LSCC	TOP2B →	+0.655	+0.203	<.001	.001	3	6
HNSC	SLC25A38 →	+0.664	+0.154	.001	.005	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,459 associations by consensus.

WDR48 vs CLASP2 — BRCA

Explore this scatter interactively →