WDR48

Across TCGA pan-cancer cohorts, WDR48 RNA is linked to patient survival in 27 of 34 cancer types, making it the most broadly survival-associated WDR48 data layer compared with 4 for mutation status and 4 for mass-spec protein.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher WDR48 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated WDR48 expression acts as an unfavorable survival marker, although some lineages such as KIRC and BRCA show a favorable association.

KIRC, BRCA, and LIHC are the cancer types where WDR48 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Tertile	All	0.745	0.556	<.001	79	view →
BRCA	DFS	Tertile	III,IV	0.942	0.788	<.001	61	view →
LIHC	DFS	Quartile	All	0.411	0.636	<.001	51	view →
ACC	DFS	Median	All	0.275	0.612	<.001	45	view →
READ	OS	Tertile	II,III,IV	0.884	0.318	<.001	42	view →
HNSC	DFS	Quartile	All	0.824	0.676	.005	41	view →
UCS	DFS	Tertile	IV	0.936	0.323	.024	36	view →
UVM	OS	Quartile	All	0.955	0.593	.005	32	view →
THYM	DFS	Quartile	All	0.965	0.765	.008	31	view →
SCLC	DFS	Quartile	II,III,IV	0.743	0.328	.007	24	view →
LGG	DFS	Median	All	0.892	0.759	<.001	23	view →
COAD	OS	Tertile	IV	0.860	0.481	.004	22	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 27 lineages.

WDR48–KIRC (DFS)

Open the KIRC breakdown →