WDR48

Across TCGA cell cohorts, WDR48 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,967 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible WDR48-associated GO terms across cancer lineages are Chemokine (C-C motif) ligand 21 signaling pathway, Positive regulation of pinocytosis, and mRNA destabilization. Each is linked with WDR48 in more than 15 cancer types. Because this analysis shows association rather than direction, both WDR48-to-partner and partner-to-WDR48 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Chemokine (C-C motif) ligand 21 signaling pathway grouped by WDR48-low versus WDR48-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (WDR48→partner) and Y-score (partner→WDR48) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Chemokine (C-C motif) ligand 21 signaling pathway →	+0.163	+0.579	<.001	<.001	3	16
LUNG_NSCLC_LUSC	Positive regulation of pinocytosis →	+0.127	+0.827	.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	mRNA destabilization →	+0.075	+0.902	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Positive regulation of double-strand break repair via homologous recombination →	+0.088	+0.990	<.001	<.001	3	14
PANCREAS	Nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay →	+0.068	+0.670	<.001	.001	3	14
LARGE_INTESTINE	Positive regulation of DNA repair →	+0.072	+0.721	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,967 associations by consensus.

Chemokine (C-C motif) ligand 21 signaling pathway by WDR48 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →