WDR45B

Across TCGA cell cohorts, WDR45B mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible WDR45B-associated genes across cancer lineages are ELOA3DP, LYZL1, and SPATA48. Each is linked with WDR45B in more than 1 cancer types. Because this analysis shows association rather than direction, both WDR45B-to-partner and partner-to-WDR45B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ELOA3DP grouped by WDR45B-low versus WDR45B-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WDR45B→partner) and Y-score (partner→WDR45B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	ELOA3DP →	+0.034	+4.273	<.001	.006	3	1
OVARY	LYZL1 →	+0.042	+4.990	<.001	.001	3	1
OVARY	SPATA48 →	+0.010	+4.807	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

ELOA3DP by WDR45B expression — LARGE_INTESTINE

Explore this box plot interactively →