WDR41

Across TCGA pan-cancer cohorts, WDR41 Mutation is linked to patient survival in 7 of 34 cancer types, making it a survival-associated WDR41 data layer compared with 27 for mass-spec protein and 6 for mass-spec protein.

The strongest signal is observed in thymoma (THYM), where higher WDR41 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated WDR41 expression acts as an unfavorable survival marker, although some lineages such as UCEC and BLCA show a favorable association.

THYM, ESCA, and HNSC are the cancer types where WDR41 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THYM	OS	Median	III,IV	0.103	0.944	<.001	42	view →
ESCA	OS	Median	II,III,IV	0.130	0.703	<.001	24	view →
HNSC	DFS	Median	All	0.187	0.710	.014	24	view →
UCEC	DFS	Median	All	1.000	0.630	.032	16	view →
KIRC	DFS	Median	All	0.146	0.808	.001	12	view →
LIHC	OS	Median	All	0.031	0.777	<.001	12	view →
BLCA	OS	Median	II,III,IV	1.000	0.411	.043	2	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

WDR41–THYM (OS)

Open the THYM breakdown →