WDR41

Across TCGA pan-cancer cohorts, WDR41 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated WDR41 data layer compared with 27 for mass-spec protein and 7 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher WDR41 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated WDR41 expression acts as an unfavorable survival marker, although some lineages such as UCEC and LUAD show a favorable association.

UCEC, CCRCC, and LUAD are the cancer types where WDR41 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Tertile	II,III,IV	1.000	0.560	.036	12	view →
CCRCC	OS	Median	All	0.643	1.000	.003	10	view →
LUAD	DFS	Median	II,III,IV	0.805	0.421	.011	7	view →
HNSC	OS	Quartile	II,III,IV	0.936	0.643	.006	3	view →
PDAC	OS	Median	IV	0.491	0.836	.024	3	view →
GBM	DFS	Median	All	0.834	0.657	.036	1	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

WDR41–UCEC (OS)

Open the UCEC breakdown →