WDR37

Across TCGA pan-cancer cohorts, WDR37 mass-spec protein is linked to patient survival in 7 of 34 cancer types, making it a survival-associated WDR37 data layer compared with 24 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher WDR37 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated WDR37 expression acts as an unfavorable survival marker, although some lineages such as PDAC and CCRCC show a favorable association.

COAD, PDAC, and CCRCC are the cancer types where WDR37 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Quartile	II,III,IV	0.782	1.000	.013	54	view →
PDAC	DFS	Median	All	0.913	0.685	<.001	47	view →
CCRCC	DFS	Median	III,IV	0.758	0.418	.004	45	view →
UCEC	DFS	Quartile	II,III,IV	0.412	0.920	.020	18	view →
LUAD	DFS	Median	III,IV	0.587	0.897	.015	16	view →
LSCC	DFS	Quartile	III,IV	0.398	1.000	.008	9	view →
GBM	DFS	Quartile	All	0.944	0.791	.035	1	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

WDR37–COAD (DFS)

Open the COAD breakdown →