WDR37

Across TCGA pan-cancer cohorts, WDR37 RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of WDR37’s most consistent transcriptional readouts.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where WDR37 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types WDR37 is over-expressed in tumor, although a few such as THCA and LUAD show the opposite, repressed pattern.

LIHC, THCA, and LUAD are the cancer types where WDR37 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in WDR37 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LIHC	Female	All	+0.810	<.001	9	view →
THCA	Male	III,IV	−0.935	<.001	8	view →
LUAD	Female	II,III,IV	−0.629	<.001	6	view →
BRCA	Female	All	−0.298	<.001	6	view →
KICH	All	All	−0.575	<.001	5	view →
COAD	All	All	−0.252	<.001	4	view →
CHOL	All	All	+1.717	<.001	3	view →
STAD	All	All	+0.326	.029	3	view →
UCEC	All	All	−0.422	.011	2	view →
PRAD	All	All	+0.353	.001	2	view →
LUSC	Male	All	−0.312	.003	2	view →
KIRP	Male	All	−0.302	.040	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

WDR37–LIHC

Open the LIHC breakdown →