WDR31

Across TCGA cell cohorts, WDR31 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,098 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible WDR31-associated GO terms across cancer lineages are Negative regulation of myoblast fusion, Regulation of organelle assembly, and Regulation of syncytium formation by plasma membrane fusion. Each is linked with WDR31 in more than 13 cancer types. Because this analysis shows association rather than direction, both WDR31-to-partner and partner-to-WDR31 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of myoblast fusion grouped by WDR31-low versus WDR31-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (WDR31→partner) and Y-score (partner→WDR31) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Negative regulation of myoblast fusion →	+0.148	+0.824	<.001	.003	3	14
STOMACH	Regulation of organelle assembly →	+0.064	+0.713	.004	.005	3	14
BLOOD_Lymphoma	Regulation of syncytium formation by plasma membrane fusion →	+0.095	+0.736	<.001	<.001	3	13
STOMACH	Regulation of autophagosome assembly →	+0.107	+1.101	<.001	<.001	3	12
STOMACH	Negative regulation of syncytium formation by plasma membrane fusion →	+0.144	+0.774	<.001	.005	3	12
OESOPHAGUS	Cilium movement involved in cell motility →	-0.109	-0.766	<.001	.002	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,098 associations by consensus.

Negative regulation of myoblast fusion by WDR31 expression — STOMACH

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