WDR26

Across TCGA pan-cancer cohorts, WDR26 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated WDR26 data layer compared with 23 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher WDR26 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated WDR26 expression acts as an unfavorable survival marker, although some lineages such as GBM and HNSC show a favorable association.

COAD, PDAC, and GBM are the cancer types where WDR26 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	II,III,IV	0.909	1.000	.011	24	view →
PDAC	DFS	Quartile	All	0.293	0.467	.023	7	view →
GBM	OS	Tertile	All	0.561	0.269	.017	5	view →
HNSC	OS	Tertile	II,III,IV	1.000	0.945	.043	4	view →
CCRCC	DFS	Median	III,IV	0.574	0.819	.031	2	view →
LSCC	DFS	Median	All	0.738	0.844	.048	1	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

WDR26–COAD (DFS)

Open the COAD breakdown →