WDR26

Across TCGA patient cohorts, WDR26 mutation is significantly associated with the total protein of many other genes, with 33 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible WDR26-associated genes across cancer lineages are PDCD4, ASNS, and mTOR_pS2448. Each is linked with WDR26 in more than 2 cancer types. Because this analysis shows association rather than direction, both WDR26-to-partner and partner-to-WDR26 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PDCD4 grouped by WDR26-low versus WDR26-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WDR26→partner) and Y-score (partner→WDR26) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PDCD4 →	-0.508	-1.874	.001	.002	3	3
UCEC	ASNS →	+0.336	+2.584	.005	.010	3	3
UCEC	mTOR_pS2448 →	-0.125	-1.986	.012	.029	3	2
UCEC	Notch1 →	+0.137	+1.584	.003	.009	3	2
UCEC	PKC-delta_pS664 →	-0.091	-2.115	.023	.016	3	2
UCEC	Shc_pY317 →	-0.153	-1.807	.002	.024	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 33 associations by consensus.

PDCD4 by WDR26 expression — UCEC

Explore this box plot interactively →