WDR25

Across TCGA cell cohorts, WDR25 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,068 significant associations in total. BONE shows the largest number of these associations.

The most reproducible WDR25-associated GO terms across cancer lineages are Vesicle budding from membrane, Endoplasmic reticulum to Golgi vesicle-mediated transport, and Regulation of ubiquitin-dependent protein catabolic process. Each is linked with WDR25 in more than 10 cancer types. Because this analysis shows association rather than direction, both WDR25-to-partner and partner-to-WDR25 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Vesicle budding from membrane grouped by WDR25-low versus WDR25-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (WDR25→partner) and Y-score (partner→WDR25) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Vesicle budding from membrane →	+0.067	+0.909	.001	.001	3	11
STOMACH	Endoplasmic reticulum to Golgi vesicle-mediated transport →	+0.075	+0.799	<.001	<.001	3	10
KIDNEY	Regulation of ubiquitin-dependent protein catabolic process →	+0.054	+0.816	<.001	.001	3	10
OESOPHAGUS	Endoplasmic reticulum to cytosol transport →	+0.169	+1.151	<.001	.001	3	9
OESOPHAGUS	Retrograde protein transport, ER to cytosol →	+0.169	+1.151	<.001	.001	3	9
OESOPHAGUS	Regulation of proteasomal protein catabolic process →	+0.081	+1.292	.007	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,068 associations by consensus.

Vesicle budding from membrane by WDR25 expression — LUNG_SCLC

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