WDR18

Across TCGA patient cohorts, WDR18 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,723 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible WDR18-associated proteins across cancer lineages are DNMT1_S714, SMC4, and YJU2. Each is linked with WDR18 in more than 5 cancer types. Because this analysis shows association rather than direction, both WDR18-to-partner and partner-to-WDR18 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, WDR18 versus DNMT1_S714 in LUAD, with a Pearson correlation of 0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (WDR18→partner) and Y-score (partner→WDR18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	DNMT1_S714 →	+0.697	+0.503	<.001	<.001	3	6
LSCC	SMC4 →	+0.458	+0.534	<.001	<.001	3	5
GBM	YJU2 →	+0.308	+0.400	<.001	<.001	3	5
OV	SGTA →	+0.381	+0.672	<.001	<.001	3	5
BRCA	MCM2_S41 →	+0.758	+0.596	<.001	.002	3	5
OV	CHAF1A →	+0.536	+0.691	.007	.003	2	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,723 associations by consensus.

WDR18 vs DNMT1_S714 — LUAD

Explore this scatter interactively →