WDR18

Across TCGA patient cohorts, WDR18 protein abundance is significantly associated with the RNA expression of many other genes, with 19,104 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible WDR18-associated genes across cancer lineages are TEX10, CCNB1IP1, and ARHGDIB. Each is linked with WDR18 in more than 7 cancer types. Because this analysis shows association rather than direction, both WDR18-to-partner and partner-to-WDR18 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, WDR18 versus TEX10 in LSCC, with a Pearson correlation of 0.75.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WDR18→partner) and Y-score (partner→WDR18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	TEX10 →	+0.761	+0.412	<.001	<.001	3	8
BRCA	CCNB1IP1 →	+0.780	+0.271	<.001	<.001	3	7
OV	ARHGDIB →	-0.904	-0.466	.001	<.001	3	6
BRCA	POLR1E →	+0.969	+0.336	<.001	<.001	3	6
HNSC	WDR12 →	+0.541	+0.197	.001	.001	3	6
HNSC	SNHG29 →	+0.949	+0.314	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,104 associations by consensus.

WDR18 vs TEX10 — LSCC

Explore this scatter interactively →