WDR17

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, WDR17 protein abundance is significantly associated with the RNA expression of many other genes, with 6,322 significant associations in total. GBM shows the largest number of these associations.

The most reproducible WDR17-associated genes across cancer lineages are HTR3B, NEGR1, and CREG2. Each is linked with WDR17 in more than 1 cancer types. Because this analysis shows association rather than direction, both WDR17-to-partner and partner-to-WDR17 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, WDR17 versus HTR3B in GBM, with a Pearson correlation of 0.72.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WDR17→partner) and Y-score (partner→WDR17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMHTR3B →+0.364+0.605<.001<.00132
GBMNEGR1 →+1.034+0.332<.001<.00132
GBMCREG2 →+1.859+0.510<.001<.00132
GBMKCNH8 →+1.088+0.361<.001<.00132
GBMPATE2 →+0.614+0.318<.001<.00132
LUADGAMTP2 →+0.414+0.896.003.00532
Each partner links to its Q-omics profile. Showing the 6 strongest of 6,322 associations by consensus.

WDR17 vs HTR3B — GBM

Per-sample scatter of WDR17 vs HTR3B in GBM (Pearson r = 0.72).

Explore this scatter interactively →

Exploration