WDR17

Across TCGA cell cohorts, WDR17 mutation is significantly associated with the RNA expression of many other genes, with 530 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible WDR17-associated genes across cancer lineages are MYOD1, CDCP2, and AWAT1. Each is linked with WDR17 in more than 1 cancer types. Because this analysis shows association rather than direction, both WDR17-to-partner and partner-to-WDR17 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MYOD1 grouped by WDR17-low versus WDR17-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WDR17→partner) and Y-score (partner→WDR17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	MYOD1 →	+1.108	+3.639	<.001	.004	3	2
CNS	CDCP2 →	+0.023	+3.273	<.001	.006	3	2
CNS	AWAT1 →	+0.049	+3.000	<.001	.006	3	2
CNS	EFCAB1 →	+0.749	+3.891	<.001	.001	3	2
LARGE_INTESTINE	ELP2 →	+0.581	+2.265	.001	.001	3	2
LARGE_INTESTINE	ZNF280D →	+0.455	+2.265	.009	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 530 associations by consensus.

MYOD1 by WDR17 expression — CNS

Explore this box plot interactively →